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Tuberculosis Notes

Medicine Notes > Clinical Respiratory Notes

This is an extract of our Tuberculosis document, which we sell as part of our Clinical Respiratory Notes collection written by the top tier of Bristol University students.

The following is a more accessble plain text extract of the PDF sample above, taken from our Clinical Respiratory Notes. Due to the challenges of extracting text from PDFs, it will have odd formatting:

Tuberculosis (TB)
? ? ? ? Definition o Causes of death of most HIV o 8200/yr; 350 deaths/yr (UK)
? ? ? ? Clinical features/Presentation o Travel high incidence TB area o Chronic cough (non-smoker) o Haemoptysis o Night sweats o Weight loss
? ? ? ? Examination findings o Reduced expansion o Dull to percussion o Reduced breath sounds o Crackles o Increased vocal resonance
? ? ? ? Diagnosis o Specific tests
? LATENT TB
?? ? ?Mantoux test- + do interferon gamma testing
? ACTIVE TB
?? ? ?CXR suggests, take sputum
?? ? ?Acid-fast bacilli resist acid on ZN staining
?? ? ?Bronchoscopy/lavage may be needed if no sputum produced
? ACTIVE NON-RESP TB
?? ? ?Samples: Sputum, pleura/pleural fluid, urine, pus, bone marrow, CSF
?? ? ?Culture
?? ? ?CXR to find coexisting resp. TB
? PCR
?? ? ?Rapid identification of rifampicin resistance
? HISTOLOGY
?? ? ?Caseating granulomas
? CXR
?? ? ?Consolidation; Cavitation; Fibrosis; Calcification
? IMMUNOLOGICAL EVIDENCE (TB skin test) o GENREAL
? Increased temp; Increased WCC/CRP; Anaemia
? ? ? ? Management o ABC o Ziehl-Nielsen/Silver stain (acid fast bacilli) o Notify authorities; Vaccinate contacts (BCG); Isolation o Test for HIV o Look for signs of spread (meningeal irritation; bones; joints; dysuria; pelvic) o Confirmed= Refer to TB service o 4 ABX
? Rifampicin & Isoniazid (4 months)

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