This is an extract of our Basal Nuclei document, which we sell as part of our Neurology Notes collection written by the top tier of Bristol University students.
The following is a more accessble plain text extract of the PDF sample above, taken from our Neurology Notes. Due to the challenges of extracting text from PDFs, it will have odd formatting:
Lecture 23 Basal Nuclei
General o BN receive large amount of input from cortex, & after processing, send it back to cerebral cortex via thalamus o Basal ganglia
? Project to ventral lateral (VLo) nucleus (thalamus)
? Provides major input to area 6 (SMA and PMA) o Cortex
? Projects back to basal ganglia
? Forms a 'loop' (Cortex?BG?Cortex) Basal nuclei o All grey matter areas buried in white matter of cerebral hemispheres technically BN
? Caudate nuclei, putamen, globus pallidus, amygdala o In terms of movement control, major components are (CORPUS STRIATUM)
? CAUDATE NUCLEUS
? GLOBUS PALLIDUS o Important connections with thalamus, subthalamic nuclei and substantia nigra o Putamen + Globus pallidus= LENTIFORM NUCLEUS o Caudate nucleus + Putamen= STRIATUM (Histologically) o Globus pallidus= PALLIDUM
? Part of pallidum migrated down midbrain= Pars Reticulata & S. Nigra Basal nuclei pathway All neurons from globus pallidus Increases activity are GABAergic in putamen
All neurons from caudate nucleus are GABAergic
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