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Normal Menstrual Cycle Puberty Notes

Medicine Notes > Gynaecology Notes

This is an extract of our Normal Menstrual Cycle Puberty document, which we sell as part of our Gynaecology Notes collection written by the top tier of University Of Leicester students.

The following is a more accessble plain text extract of the PDF sample above, taken from our Gynaecology Notes. Due to the challenges of extracting text from PDFs, it will have odd formatting:

Normal Menstrual Cycle Overall control of the menstrual cycle is my hormones in the hypothalamic-pituitary-ovarian cycle Hypothalamus


Anterior pituitary



Oestrogen +
progesteronePulsatile release of GnRH stimulates the release of LH + FSH Moderate titres of oestrogen inhibit GnRH release High titres of oestrogen (pure) promote GnRH secretion causing the LH surge Progesterone enhances the inhibitory effect of moderate titres of oestrogen + prevents positive feedback of pure oestrogen

Day 1 = 1st day of menstrual bleed Follicular/proliferative phase = day 0-12
- Follicles grow in ovary
- Uterus prepared for sperm transport and implantation of conceptus
- Changes occur to facilitate sexual interactions
- FSH looks after gamete and makes it grow
- LH stimulates hormone production
- Oestrogen stimulates o Fallopian tube function o Thickening of endometrium o Growth + motility of myometrium o Thin alkaline cervical mucus (to draw sperm out of semen) o Vaginal changes o Changes in skin, hair and metabolism
- LH surge stimulates ovulation Ovulation = day 12-14
- Breif period of fertility
- Formation of corpus luteum Luteal/secretory phase = day 14-28
- Corpus luteum formed in ovary grows under influence of LH o Dies after 14 days if no signal of pregnancy is received
- Progesterone o Acts on oestrogen primed cells causing further thickening of endometrium into secretory form o Thickening of the myometrium but reduced motility o Thick acidic cervical mucus o Changes in mammary tissue o Raised body temperature

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