This is an extract of our Leukaemia document, which we sell as part of our Haematology Notes collection written by the top tier of University Of Leicester students.
The following is a more accessble plain text extract of the PDF sample above, taken from our Haematology Notes. Due to the challenges of extracting text from PDFs, it will have odd formatting:
Leukaemia Unregulated proliferation of a clone of immature blood cells Aetiology
- Chromosomal abnormalities o Translocations
? Philadelphia chromosome found in 95% of CML
? Translocation between 9 + 22
? Involves bcr-abl genePredisposing factors o Radiation exposure o Previous chemotherapy (especially alkylating agents) o Exposure to benzenes o Down syndrome
Classification Leukaemia Acute Myeloid Lymphoblastic Lymphocytic
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