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Cancers Of The Gi Tract Notes

Medicine Notes > Oncology Notes

This is an extract of our Cancers Of The Gi Tract document, which we sell as part of our Oncology Notes collection written by the top tier of University Of Leicester students.

The following is a more accessble plain text extract of the PDF sample above, taken from our Oncology Notes. Due to the challenges of extracting text from PDFs, it will have odd formatting:

Cancers of the GI tract Carcinoma of the stomach Associations
- Blood group A
- H. Pylori - chronic gastritis - atrophic gastritis - intestinal metaplasia
- Smoking
- High salt diet Pathogenesis
- Most occur in antrum
- P53 and APC affected
- Commonly 'intestinal' (intestinal metaplasia seen in surrounding mucosa)
- Adenocarcinoma Clinical features
- Epigastric pain
- Nausea
- Anorexia
- Weight loss
- Vomiting (severe if near pylorus)
- Dysphagia (if involves fundus)
- Anaemia
- Mets to liver, bone, brain + lung Investigations
- Bloods o FBC (anaemia) o Liver biochem
- Imaging o CT/MRI staging o Gastroscopy and biopsies Management
- Surgery
- Chemotherapy
- Radiotherapy
- Palliative care
- 5 year survival <10%

Signs
- Palpable epigastric mass
- Vichow's node

Buy the full version of these notes or essay plans and more in our Oncology Notes.