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Spondyloarthropathies Notes

This is a sample of our (approximately) 6 page long Spondyloarthropathies notes, which we sell as part of the Rheumatology Notes collection, a MBChB (hons) (1st) package written at University Of Leicester in 2014 that contains (approximately) 20 pages of notes across 6 different documents.

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Spondyloarthropathies Revision

The following is a plain text extract of the PDF sample above, taken from our Rheumatology Notes. This text version has had its formatting removed so pay attention to its contents alone rather than its presentation. The version you download will have its original formatting intact and so will be much prettier to look at.

Sero-negative inflammatory arthritis (Spondyloarthropathies) A group of inflammatory conditions, which typically affect the spine and enthesis (tendon and ligament insertions) Associated with HLA-B27 gene Distinct from RA because
- Seronegative (no RF)
- Males> Females
- Younger patients Includes
- Ankylosing spondylitis
- Psoriatic arthritis
- Reactive arthritis

Ankylosing Spondilitis A chronic inflammatory disorder with eventually leads to ankylosis (fusion). Mainly affects the spine but can invade proximal joints of limbs Pathogenesis
- Chronic inflammation of synovium, articular cartilage and ligaments
- Leads to ossification of joints
- After 10-15 years inflammation stops and disease process halts Diagnostic criteria 1) Limitation of movement of lumbar spine in all 3 planes 2) Hx of pain in lumbar spine or at the dorso-lumbar junction 3) Limited chest expansion to

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