This is a sample of our (approximately) 6 page long Spondyloarthropathies notes, which we sell as part of the Rheumatology Notes collection, a MBChB (hons) (1st) package written at University Of Leicester in 2014 that contains (approximately) 20 pages of notes across 6 different documents.
The original file is a 'Word (Docx)' whilst this sample is a 'PDF' representation of said file. This means that the formatting here may have errors. The original document you'll receive on purchase should have more polished formatting.
The following is a plain text extract of the PDF sample above, taken from our Rheumatology Notes. This text version has had its formatting removed so pay attention to its contents alone rather than its presentation. The version you download will have its original formatting intact and so will be much prettier to look at.
Sero-negative inflammatory arthritis (Spondyloarthropathies) A group of inflammatory conditions, which typically affect the spine and enthesis (tendon and ligament insertions) Associated with HLA-B27 gene Distinct from RA because
- Seronegative (no RF)
- Males> Females
- Younger patients Includes
- Ankylosing spondylitis
- Psoriatic arthritis
- Reactive arthritis
Ankylosing Spondilitis A chronic inflammatory disorder with eventually leads to ankylosis (fusion). Mainly affects the spine but can invade proximal joints of limbs Pathogenesis
- Chronic inflammation of synovium, articular cartilage and ligaments
- Leads to ossification of joints
- After 10-15 years inflammation stops and disease process halts Diagnostic criteria 1) Limitation of movement of lumbar spine in all 3 planes 2) Hx of pain in lumbar spine or at the dorso-lumbar junction 3) Limited chest expansion to <2.5cm measured at 4th ICS 4) Sacroilitis - must have this +/- other symptoms Clinical features Early symptoms
- LBP (worse at night, gradual onset)
- Stiffness relieved by exercise
- Pain may progress up the back, SIJ, hips and down legs Examination
- Limited lumbar spine movement
- Decreased chest expansion (ankylosis of costovertebral joints)
- Enthesis - usually Achilles tendon or plantar fascia Schobar test for lumbar flexion
- Pt stands erect. Make mark over spinous process of L5 - make another mark 10cm above it and ask pt to bend forward. Distance normally exceeds 15cm Wall test for cervical flexion deformity
- Pt stands erect with heels and buttocks against wall
- Instruct pt to extend neck maximally in attempt to touch wall with the occiput. Distance between occiput and wall measures degree of deformity Extra-articular features Eyes - Uveitis Heart - Aortitis, cardiomegaly Lungs - Apical pulmonary fibrosis Renal - IgA nephropathy, amyloidosis GI - Inflammatory bowel disease Limbs - Neuropathy
****************************End Of Sample*****************************
Buy the full version of these notes or essay plans and more in our Rheumatology Notes.