Medicine Notes Paediatrics Notes
Paediatric notes based upon current NICE guidance, The Illustrated Textbook of Paediatrics by Lissauer and Clayden in conjunction with the Oxford Handbook of Paediatrics...
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Musculoskeletal
pGALS
Screening Questions “Do you (or you child) have any…”
Pain or stiffness in your muscles, joints or back?
Difficulty getting dressed without help?
Difficulty going up and downstairs?
Posture and Gait
Observe standing
Observe walking
Heel walking*
Tip-toes*
Arms
Put your hands out straight in front of you
Turn your hands over
Make a fist
Pincer grip
Touch the tips of your fingers to your thumb
Squeeze the MCP joints for tenderness
Put your hands behind your head
Hands together palm to palm*
Hands together back to back*
Reach up and touch the sky now look at the ceiling*
Legs
Feel for effusion of the knee
Bend and straighten your knee feel for crepitus
Passive movement of hip
TMJ
Open mouth and move about
Neck and Spine
Touch ear to shoulder lateral flexion of cervical spine
Bend forward and touch your toes observe curve of spine
* Differences from adult GALS
Regional MSK Assessment
Look
Signs of discomfort
Skin abnormalities
Limb alignment, muscle bulk, asymmetry
Bone deformity, swelling
Feel
Each joint, bone and neighbouring soft tissue
Warmth – infection or inflammation
Delineate swelling
Check for effusion at knee
Move
Active followed by passive
Compare sides
Function
Gait
Grip
Arthritis
Causes of Polyarthritis
Infection
Bacterial
Viral rubella, mumps, adenovirus, herpes, hep, parvovirus
Other mycoplasma
Reactive GI infection, streptococcal
Rheumatic fever
Inflmmatory Bowel Disease
Vasculitis HSP, Kawasaki disease
Haematological Disorders haemophilia, sickle cell
Malignant leukaemia, neuroblastoma
Connective Tissue Disorders
Juvenile idiopathic arthritis
SLE
Dermatomyositis
Polyarteritis nodosa
Other CF
Reactive Arthritis
Clinically
Transient joint swlling (<6 weeks)
Often ankles or knees
Typically follows extra-articular infection
Enteric bacteria in children salmonella, shigella, camplyobacter, yersinia
In adolescents chlamydia, gonococcus, mycoplasma, Lyme disease
Rheumatic fever in developing countries
Low grade fever
Investigations
Fever
Acute phase reactants are normal or mildly elevated
XR normal
Treatment
Supportive
NSAIDs
Septic Arthritis
Serious infection of the joint space
Common in children <2 years
Typically one joint, hip is common
Pathogenesis
Typically results from haematogenous spread
May occur following puncture wound or infected skin lesion
In young children if may result from spread from adjacent osteomyelitis into joints where the capsule inserts below the epiphyseal growth plate
Causative Organisms
<12 months old; Staph, Group B strep, gram nevative bacilli
1-5 years; S aureus, Hib, Group A strep, Strep pneumoniae
5-12 years; S. aureus, Group A strep
12-18 years; S. aureus, Gonorrhoeae
Consider underlying illness immunodeficiency and sickle cell
Presentation
75% of cases involve the lower limb (knee>hip>ankle)
Erythamatous, warm, tender joint
Reduced range of movement
Unwell, febrile child
Pseudoparesis Characteristis posture to reduce intracapsular pressure
Leg is held flexed, abducted and externally rotated
Investigation
Increased WCC, acute phase reactants
Blood cultures
USS to identify effusion
XR exclude trauma and other bony lesions
In septic arthritis XR is initially normal except widened joint space
MRI scan may demonstrate adjacent osteomyelitis
USS guided aspiration from the joint space and culture is GOLD standard
(? lumbar puncture if septic joint with Hib)
Treatment
IV antibiotics for 3 weeks followed by oral for a total of 4-6 weeks
Surgical irrigation and debridement
May require immobilisation
Onset – acute, non weight bearing
Fever – moderate, high
Child’s appearance – looks ill
Hip movement – held flexed, severe pain at rest and worse on attempts to move
WCC – normal/high
CRP/ESR – raised
USS – fluid in joint
Radiograph – normal / increased joint space
Rx – joint aspiration, prolonged antibiotics, rest and analgesia
Course – progressive and severe joint damage if untreated
Juvenile Idiopathic Arthritis (JIA)
Commonest chronic inflammatory joint disease in children and adolescents in the UK (1/1000)
Defined as persistent joint swelling (>6 weeks) presenting before 16 years of age. In the absence of infection or any other defined cause
1 in 1000 children
Seven subtypes based on the number of joints affected in the first 6 months:
Polyarthritis; >4 joints
Oligoarthritis; up to and including 4 joints
Systemic; with fever and rash
Psoriatic arthritis
Enthesitis
Subtype is further classified according to the presence of rheumatoid factor and HLA B27
Features in the history
Gelling (stiffness after periods of rest)
Morning joint stiffness and pain
In the young child intermittent limp or deterioration in behaviour, mood or avoidance of once enjoyed activities
Swelling and inflammation of the joint
Proliferation of the synovium
Periarticular swelling
Long term in uncontrolled disease bone expansion from overgrowth leg lengthening or valgus deformity, discrepancy in digit length. Etc.
Complications
Chronic anterior uveitis
Flexion contractures of the joints
Growth failure generalised from anorexia, chronic disease and systemic corticosteroid therapy
Constitutional problems anaemia of chronic disease, delayed puberty
Oseroporosis multifactorial – diet, reduced weight bearing, systemic corticosteroids and delayed menarche
Amyloidosis v. rare, causes proteinuria and renal failure
Management
Physio
Links with opthalmology, dentistry (risk of caries) and orthopaedics
Medical management
NSAIDs and analgesia
Joint injections esp in oligoarticular JIA. Bridging assesst before methotrexate in polyarticular disease
Methotrexate
Weekly
Monitor bloods abnormal LFTs and bone marrow suppression
Systemic corticosteorids
Avoid if necessary to avoid growth suppression and osteoporosis
Pulsed IV methylprednisolone for severe polyarthrtitis
Biologics – cytokine modulators and other...
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Paediatric notes based upon current NICE guidance, The Illustrated Textbook of Paediatrics by Lissauer and Clayden in conjunction with the Oxford Handbook of Paediatrics...
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