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e-learning II - 3D Drug Targets
Organic compounds that have the same molecular formulae but have different three-dimensional structures are termed isomers.
There are several different types of isomerism, some of which you may already have come across:
(eg: pentan-1-ol and pentan-2-ol). These compounds differ in the order the atoms are connected.
Stereoisomers are compounds that have the same functional groups and bonding pattern but differ in the three-dimensional arrangement of atoms in space.
There are several different subtypes of stereoisomerism:
(eg: chair and boat forms of glucose). These are different conformations of the same compound and can be readily interconverted by bond rotation.
(eg: cis (I) and trans (II) dichloroethene). These compounds differ in their orientation around a double bond.
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