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Veterinary Medicine Notes Small Animal Internal Disease - Skin Notes

Skin Diseases Miliary Dermatitis Eosinophilic Plaque Eosinophilic Complex Notes

Updated Skin Diseases Miliary Dermatitis Eosinophilic Plaque Eosinophilic Complex Notes

Small Animal Internal Disease - Skin Notes

Small Animal Internal Disease - Skin

Approximately 40 pages

These notes cover the internal disease section of my state final exam. This section (Skin) includes;

1. Skin Diseases - Pyoderma, Pyotraumatic Dermatis, Superficial and Deep Folliculitis, Furunculosis, Pododermatitis.
2. Skin Diseases - Alopetic
3. Skin Diseases - Pruritic
4. Atopy, Flea Allergy, Food Sensitivity.
5. Skin diseases of cats - milliary dematitis, eosinophilic complex.
6. Ear Disease - Otitis Externa, media, interna, and skin adnexae
7. Tumours of the skin and subcutis

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The following is a more accessible plain text extract of the PDF sample above, taken from our Small Animal Internal Disease - Skin Notes. Due to the challenges of extracting text from PDFs, it will have odd formatting:

5. Skin Diseases: Miliary dermatitis, eosinophilic complex

Feline military dermatitis (FMD) and Eosiniphilic Granuloma Complex (EGC) are extremely common cutaneous reaction patterns in the car

MD Papules and crust of this disease resemble millet seeds

EGC lesions affect the skin and oral cavity.

  • Includes eosinophilic ulcer, eosinophilic plaque and eosinophilic granuloma

Etiology

Neither MD or EGC are a final diagnosis, nor are they pathognomic for any one disease

Allergies Biting insects, food, environmental allergens and rarely contact substances

  • Fleas and other biting insects emphasized in EGC etiology

Parasites Fleas, demodex, cheyletiella, Notoedres, Otodectes – assoc with MD

  • Fleas implicated in EGC

Infectious Diseases Staph, Strep, Pasteurella, Bacteriodes

  • Dermatophytes Microsporum Canis

  • MD Consider Malassezia

  • EGC Viral conditions are an added consideration

Miscellaneous

  • MD Genetic, Immune-mediated diseases, Drug reactions, Nutritional, Idiopathic

  • EGC Genetic, Immune-mediated, Idiopathic

  • Immune mediated e.g. Pemphigus foliaceus

  • Nutritional e.g. biotin or F.A. deficiencies

Pathogenesis of EGC:

  • Pathogenic events in these lesions are most likely caused by eosinophil recruitment and degranulation. Circulating eosinophils move into tissues in reaction to inflammation prompted by antigen-antibody complexes, parasites, or microorganisms.

  • Since eosinophils are attracted to and phagocytize antigen-antibody complexes, the presence of eosinophils in the EGC indicates that it is an immune-mediated disease

Clinical Signs

Miliary Dermatitis

  • Lesions small erythematous papules that develop into crusts

  • 20 lesions arise from self trauma and produce alopecic erosions and excoriations

  • Distribution localized or generalized. Dorsal lumbosacral, cervical and inguinal regions mostly.

    • If head and neck are affected, consider notoedric/otodectic mange, food allergy, atopic dermatitis, pyoderma

  • Additional signs Peripheral lymphadenopathy of the inguinal L.N., Depression, Pain and twitching over affected areas

Eosinophilic Granuloma Complex

Eosinophilic Ulcer

  • (indolent, rodent and lip ulcer) Well circumscribed, red-brown to yellow, ulcerated

  • Most commonly on upper lip

  • Generally non painful and non pruritic

Eosinophilic Plaque

  • Wel...

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