Medicine Notes Respiratory System Notes
These notes are on the Respiratory System of the human body. helped me achieve a mark of 68% in my respiratory exam, which is the equivalent of a 2:1. The notes are based on a series of lectures on the subject. They are very clearly laid out and easy to follow. They cut out unnecessary information on the topic, making the notes very concise, and fast to get through. Anyone studying medicine, or any other subject requiring knowledge of the Respiratory system (e.g. physiology or anatomy), would ben...
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Lecture 9
Respiratory homeostasis and abnormalities
Apply Fickโs principle to solve problems involving CO and oxygen consumption
Blood flow to organ can be calculated using marker substance if following is known
Amount of marker substance taken up by the organ per unit time
Concentration of marker substance in arterial blood supplying the organ
Concentration of marker substance in venous blood leaving the organ
Oxygen Consumption Rate (Vo2)
Measured using spirometer or calculated using Fick principle:
Vo2 = Cardiac output x (CaO2 โ CvO2)
Depends upon cardiac function (ETT) andability of tissues to extract oxygen.
Describe & explain changes in respiratory rate, tidal volume, CO, oxygen consumption & CO2 that occur during exercise
PAO2, PaO2, CO2 & oxygen saturation all unchanged
Increased ventilation (tidal volume, respiratory rate, CO & O2 consumption increase)
Outline theories regarding alteration to control of ventilation during exercise
Chemoreceptors in veins that havenโt been found yet
Increase in body temperature (not much evidence)
Activity in motor cortex= increased respiratory centre activity
Receptors in muscle spindles and joints (tandem bike test, one pedalling but both ventilation goes up)
Chemoreceptors more sensitive in exercise so sense small changes
Define and explain VO2 max. Using Fick principle to explain determining factors
Maximum capacity of an individual's body to transport and use oxygen during incremental exercise, which reflects the physical fitness of the individual
Factors affecting VO2 are often divided into supply and demand factors
Supply (usually limiting one)
Transport of oxygen from the lungs to the mitochondria
Lung diffusion, stroke volume, blood volume, & capillary density of muscle
Demand
Rate at which the mitochondria can reduce O2 in the process of oxidative phosphorylation
Describe and explain anaerobic threshold stating the effect upon plasma lactate concentration and minute ventilation
Calculate the rate of oxygen delivery to systemic tissues
Greater delivery than consumption
So, if arterial levels drop, there is no real danger
Factors that determine oxygen delivery to tissue
Blood flow (in terms of CO)
Oxygen content in arterial blood (amount of O2 dissolved & bound to haemoglobin can be calculated)
List the symptoms and signs of acute hypoxia
Symptoms
Euphoria, fatigue, headache, light-headedness, tunnel vision, anorexia
Signs
Ataxia, convulsions, confusion, tachy, swearing &...
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These notes are on the Respiratory System of the human body. helped me achieve a mark of 68% in my respiratory exam, which is the equivalent of a 2:1. The notes are based on a series of lectures on the subject. They are very clearly laid out and easy to follow. They cut out unnecessary information on the topic, making the notes very concise, and fast to get through. Anyone studying medicine, or any other subject requiring knowledge of the Respiratory system (e.g. physiology or anatomy), would ben...
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