This is a sample of our (approximately) 3 page long Mitosis notes, which we sell as part of the Organisation of the Body Notes collection, a First package written at Oxford in 2014 that contains (approximately) 257 pages of notes across 38 different documents.
The original file is a 'Word (Docx)' whilst this sample is a 'PDF' representation of said file. This means that the formatting here may have errors. The original document you'll receive on purchase should have more polished formatting.
The following is a plain text extract of the PDF sample above, taken from our Organisation of the Body Notes. This text version has had its formatting removed so pay attention to its contents alone rather than its presentation. The version you download will have its original formatting intact and so will be much prettier to look at.
-Cells undergo cell division- to replace cells that have been lost due to maturation/apoptosis
-cells also divide- inresponse to an increased work load
-seen by light microscope- labelled radioactive DNA precursors such as H3 Thymidine- recorded using autoradiographic methods G0 phase
-most of the cells in this phase are differentiated- specific function
-to leave this phase requires growth factors Progression through the cell cycle is dependent by cyclin dependent kinase which phosphorylates other substrates and promote cell divison G1
-longest and most variable cell cycle phase- determines the length of the whole cycle
-requires continuous signals from growth factors
-large amount of growth- large amounts of RNA and protein synthesis
-restriction point at the end of G1 phase- determines whether cell can enter S phase- cell size, condition of the chromosomes, external environment or enter the G0 phase
-p53 stimulates the G1 phase to progress onto S phase S
-all replication needed to create two cell occurs- DNA and organelles
-synthesis of DNA, replication of centrosomes
-centrosomes are key for cell division - each consists of two centiroles- barrels of 9 triplet microtubules G2
-phase of chromosome packaging
-synthesis of proteins required for mitosis
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