Eating disorders
Classification of eating disorders
Anorexia nervosa
Bullimia nervosa
Binge eating
Otherwise specified feeding/ eating disorders ED-NOS
Core features: disturbed eating; over evaluation of control of eating, weight, shape- resulting in clinically significant impairment in health and psychosocial function. Also not secondary to any general medical/ psychiatric condition
Common risk factors
Compulsivity – trait; aberrant sense of reward
Genetics
Female
Adolescence
Depression
substance misuse, alcoholism (more for BN)
Obesity (BN)
Premorbid experiences
Adverse parenting- low contact; high expectations; parental discard
Sexual abuse
Family dieting
Critical comments about eating, weight and shape from others
Occupational pressure to be slim- such as in ballets- more so for BN
Early menarche (period) – more so for BN
Pre morbid characteristics
Low self esteem
Perfectionism (AN)
Anxiety and anxiety disorder – not eating feels better
Overlap between the three disorders mean people cross into other categories over time. Due to the similarities a transiagnostic form of CBT has been developed for full range of eating disorders. This is based on transdiagnostic theory of maintainence
Anorexia nervosa
Incidence and prevalence
Highest mortality rate of any psychiatric disorder
Incidence is 8 per 100,000
90% Female
Adolescents: 0.3% in teenage girls
Excess in higher social classes
Diagnosis
Refusal to maintain body weight over a minimally normal weight for age and height
Intense fear of gaining weight or becoming fat, even though underweight
Undue influence of body weight or shape on self evaluation or denial of seriousness of the current low body weight
In female, absence of least 3 consecutive menstrual cycles when otherwise expected to occur (this has now been removed from DSM-V)
Subtypes:
Restricting type- during the last 3 months person has not engaged in recurrent episodes of binge eating or purging behaviour
Binge/Purge type: During the last 3 months, person has engaged in recurrent episodes of binge eating or purging behaviour
Clinical features- very low BMI
Severe mood swings
Lack of energy and weakness
Slowed thinking; poor memory; Dizziness, fainting, headaches
Dry yellowish skin, brittle nails; Growth of fine hair all over the body and face
Constipation and bloating
Tooth decay and gum damage
Treatment
Target compulsivity due to aberrant reward processing/ corticostriatal circuits common to compulsive disorders
Training cognitive flexibility
Reducing pre-occupation
Training interoceptive/ somatic awareness
Novel medications acting on reward/ compulsivity pathways
Characterise neural circuits with state of art neuroimaging
Intervening with neural circuits- neuromodulation- deep brain stimulation
Current managmenet
Help patients see they need help and to maintain motivation
Help patients reverse starvation and restore weight
Adressing compulsivity and over-evaluation of shape, weight and control over eating
Cogntivie behavioural therapy- there isn’t a strong evidence base for treatment using CBT
Compulsory treatment only relevant in few cases Drug treatment doesn’t currently have established role
Bullimia
Incidence and prevalence
12 per 100,000
Western society
Mostly female
Young adults rather than adolescents
Diagnosis- DSM-V
Eating in discrete period of time an amount of food that is larger than most people would eat during a similar period of time and under similar circumstances
Sense of lack of control over eating during the episode- feeling that one can’t stop eating/control how much one is eating
Recurrent inappropriate compensatory behaviour to prevent weight gain, such as self induced vomiting, misuse of laxative, diuretics, enemas, or other medications, fasting
Binge eating and inappropriate compensatory behaviour both occur on average at least once a week for 3 months
Types
Purging type: During the current episode of Bulimia Nervosa the person has regularly engaged in self induced vomiting or misuse of laxative, diuretics or enemas
Non purging type: Other inappropriate compensatory behaviour
Clinical features
Chronic gastric reflux after eating
Dehydration and hypokalaemia caused by frequent vomiting
Electrolyte imbalance cardiac arrhythmia, cardiac arrest
Esophagitis, rupture of oesophageal due to vomiting
Constipation
Treatment
Grade A: specific form of cognitive behavioural treatment – 1/3rd to make complete recovery
Grade B : Interpersonal psychotherapy / trial of anti-depressant
Binge eating
Incidence and prevalence
Later onset; higher proportion in men
Diagnosis
Recurrent periods of binge eating
> weekly for > 3 months
No compensatory behaviours
No over evaluation of control of eating, weight and shape
Treatment
Cognitive behavioural therapy
Empirical evidence starvation studies
Minnesota study- Keys et al 1950
36 young healthy men
3 month baseline
6 month period of severe dietary restriction (50%) prior intake
3 month re-feeding phase
Key changes
Preoccupation...