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Cancer And Histology Notes

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This is an extract of our Cancer And Histology document, which we sell as part of our Medical Finals & OSCEs Notes collection written by the top tier of Oxford University students.

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Cancer and Histology Adenocarcinoma=neoplasia of epithelial tissue of glandular origin Carcinoma=neoplasia of epithelial tissue Carcinoma-in-situ=neoplasia of epithelial tissue that has not (yet) eroded through the basement membrane Squamous cell carcinoma=neoplasia of epithelial tissue of squamous cells Sarcoma=cancer of connective tissue Cancer

Histological classification/Cell type


Ductal adenocarcinoma

Pancreatic (MEN1)

Insulinoma, gastrinoma, glucagonoma, non-functioning



Non-invasive ductal carcinoma-in-situ (premalignant)


Non-invasive lobular carcinoma-in-situ (premalignant)


Invasive ductal carcinoma (70% of all breast cancers)


Invasive lobular carcinoma


Medullary carcinoma


Colloid cancer


Tubular cancer



Paget's disease of the breast

Thought to be ductal carcinoma-in-situ


Clear cell carcinoma/renal cell carcinoma (vHL)

Kidney in sickle cell trait

Renal medullary carcinoma


Urothelial cell carcinoma/transitional cell carcinoma

Bladder (schistosomiasis)

Squamous cell carcinoma



Prostatic intraepithelial neoplasia/PIN

Premalignant carcinoma-in-situ that develops into prostatic adenocarcinoma


Commonest: papillary thyroid cancer Second commonest: follicular thyroid cancer

Thyroid (MEN2A/B)(NF1)

Medullary thyroid cancer

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