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The Principle of Supremacy: EU law is supreme over domestic law
Costa v ENEL 
EU legal order is distinct from all other legal systems.
EU law is an integral part of domestic law.
MSs have limited their sovereign rights, albeit within limited fields, and have thus created a body of law which binds both their nationals and themselves.
EU law is supreme because ether member states wished it to be so.
This is a teleological and textual approach.
o Internationale Handelsgesellschaft 
At the time was considered that EU had nothing to do with Human Rights
Held Scope of supremacy is unlimited, any EU law takes precedence over any national law, other EU law would not be effective.
Enactment of Supremacy
Internationale Handelsgesellschaft 
Alleged clash between and EU regulation and the principle of proportionality which was protected under the German constitution.
Respect for fundamental rights forms an integral part of the general principles of law protected by the Court of Justice.
o Simmenthal II 
Were inspections carried out on the Italian boarder compatible with EU law - no.
"every national court must, in a case within its jurisdiction, apply Community law in its entirety and protect rights which the latter confers on individuals and must accordingly set aside any provision of national law which may conflict with it, whether prior or subsequent to the Community rule."
Individuals gain rights at the cost of MSs sovereignty
EU measures are immediately effective, need not wait until the measure is set aside.
o Reflects Art. 4(3) TEU: : "Member States shall take any appropriate measure, general or particular, to ensure fulfilment of the obligations arising out of the Treaties"
o Factortame (I)  - Procedural problem in so far as the court in question was not allowed to provide interim relief as was being requested by plaintiffs.
It follows that a court which in those circumstances would grant interim relief, if it were not for a rule of national law, is obliged to set aside that rule.
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