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Reticular Formation Notes

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Lecture 46 Reticular Formation

Location o Midbrain- Mesencephalic RF (neurons scattered around here) o Pons- Pontine RF (adjacent to 4th ventricle) o Medulla- Medullary RF Afferent/Efferent o Afferent
 Sensory pathways (optic, auditory, olfactory)
 Thalamus
 Cerebellum
 Corpus striatum
 SC (touch, pain, temperature)
 Cortex o Efferent
 Cortex (main)
 Cerebellum
 Substantia nigra; Red nucleus
 Tectum
 SC
 Thalamus/hypothalamus Connections o Local projections
 Local-circuit interneurons
 Functions

• Reflexice and stereotyped behaviours of head and face o Chewing, swallowing, vomiting o Respiratory (coughing, hiccups, sneezing) o o

CVS responses (heart rate, BP)

Long projection systems

Ascending to cortex (reticular activating system)

Functions o o

Alertness and consciousness

o

Sleep-wake cycle

Wakefulness

Descending to spinal cord

Functions o

Posture and ANS activity

o o

Sensory (pain) anaesthetics)

&

motor

modulation

(target

Info from hypothalamus (connected to endocrine systems)

Functions o

SENSORY & MOTOR FUNCTIONS

Organising, co-ordinating and regulating reflexes


o

Gating and modulating info transfer

Reticulospinal tracts

AUTONOMIC AND VITAL FUNCTIONS

Regulations of ANS (input on everything innervated by ANS)

CVS regulation

for

Control respiration

Neurotransmitter systems o

Specific group of neurotransmitters

CNS

neurons

o

NA; A; DA; 5HT; Histamine= MA

use

ACh

Cell bodies can be localised and axons traced

monoamines

and

ACh

as

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